What is a CT-Guided Biopsy?

A CT-guided biopsy is a safe, minimally invasive procedure that uses a CT scan to guide a small needle into a specific area of the body. It helps doctors collect a tissue sample to diagnose or rule out diseases — without needing open surgery.This biopsy is usually done when there's a lump, tumour, or abnormal spot that needs closer examination.

Why is it done?
  • To check if a lump is cancerous or benign
  • To diagnose infections or inflammation
  • To plan proper treatment based on accurate results
How to Prepare

To keep you safe and ensure the best results, here’s what you need to know before your appointment:

The day before:

  • Fasting: Don’t eat or drink anything except water for at least 6 hours before the scan. If your appointment is in the morning, stop eating from midnight.
  • Medicines: Avoid aspirin, ibuprofen, and vitamin E for 3–7 days before the procedure. Talk to your doctor about any medications you are on.
What to bring:
  • Your recent medical records and prescriptions
  • Any reports about diabetes or blood-related conditions
  • A serum creatinine report (not older than 4 weeks) – this is to check kidney function if a contrast dye is used
What to wear:
  • Loose, comfortable clothing
  • No jewellery, metal clips, or accessories

For women:

  • Let your doctor know if you are pregnant or breastfeeding
  • If you’re breastfeeding and a contrast dye is used, pump and store milk in advance. Avoid breastfeeding for 24 to 48 hours after the scan

Bring a companion:
Please come with one family member or friend to support you during the visit

How Long Does it Take?

The entire visit can take around 4 to 5 hours. Here's a rough timeline:

Step Time
Patient history & consent 5–10 mins
Medicine preparation 10–15 mins
Waiting time (if contrast is used) 45–60 mins
Scan and biopsy on table 15–20 mins
Post-scan observation 5–10 mins
What Happens During the Procedure?

Changing and prep:
You’ll change into a gown and remove any metal items. If contrast dye is needed, it will be given through an injection or by mouth.

Waiting (if oral contrast is given):
You may need to wait about an hour for the dye to circulate.

In the scan room:
You’ll lie on a flat table that moves into a CT scanner (a doughnut-shaped machine). The technician will guide you from another room and stay in constant contact through an intercom.

During the scan:
The CT machine takes detailed images of your body. You’ll need to stay very still and may be asked to hold your breath briefly.

Biopsy:
Using the CT images, the doctor will gently insert a fine needle into the exact spot and collect a small tissue sample. This part is carefully guided and usually causes only mild discomfort.

After the scan:
You’ll be monitored for a short while to ensure you feel fine, especially if contrast dye was used.

After the Biopsy

You may feel a little sore at the biopsy site for a day or two. Rest is recommended for the same day. Your doctor will explain when you can resume normal activities.

When Will I Get the Results?

The tissue sample is studied by a pathologist. Your doctor will share the results and next steps with you, usually within a few days.

Need to Ask Something?

Our team at Mumbai Diagnostic Centre is here to help. Feel free to ask us anything — before, during, or after your visit.